Informazioni offerta

ABB

Sede

Settore/Area di riferimento

Numero di posizioni disponibili

Tipologia contrattuale

Descrizione

Organizational Unit: Pre-clinical R&D – Pharmacokinetic Biochemistry & Metabolism

Responsibilities: Carrying out in vitro ADME studies for Discovery and Early Development projects

Activities: Development of bioanalytical methods for in vitro ADME studies

• Planning and conducting in vitro metabolism studies (Clint in hepatocytes and microsomes, metabolic stability in S9 and plasma etc)

• Planning and conducting CYP450 interaction and induction studies in vitro • Reaction phenotyping for enzymes responsible for metabolism

• Preparation of reports on the analyses carried out

• Biodistribution studies

Education: Degree in CTF or similar

Experience: At least 3 months of experience in an In Vitro Metabolism Laboratory of a pharmaceutical industry or a university.

Technical skills:

• Instrumentation: HPLC-MS/MS is a must.

• Knowledge of microplate reader, PCR, optical and fluorescence microscope, cell culture techniques, in vitro ADME models will be an asset.

Soft skills:

• autonomy

• analytical capacity

• results orientation

• team working

• attention to quality

Languages: good english

Contract type: maternity leave

Place of work: Parma, Italy